William Culpepper
William Culpepper may refer to:
- William T. Culpepper III, American politician
- William Colepeper, English politician and poet
- Sir William [Culpeper, 1st Baronet of Preston Hall], of the Culpeper baronets
- Sir William Culpeper, 1st Baronet of Wakehurst, of the Culpeper baronets
- Sir William Culpeper, [4th Baronet], of the Culpeper baronets