William Clayton
William Clayton may refer to:
Politics
United Kingdom
- William Clayton (Liverpool MP), Member of Parliament for Liverpool, 1698–1708
- Sir William Clayton, 1st Baronet, Member of Parliament for Bletchingley, 1715–1744
- William Clayton, 1st Baron Sundon, MP for Woodstock, St Albans, Westminster, Plympton Erle and St Mawes
- William Clayton (died 1783), MP for Bletchingley, 1745–1761, and Great Marlow, 1761–1783
- Sir William Clayton, 4th Baronet, Member of Parliament for Great Marlow, 1783–1790
- Sir William Clayton, 5th Baronet, Member of Parliament for Great Marlow, 1832–1842
United States
- William F. Clayton, US politician
- William C. Clayton, American educator, lawyer, politician, and businessperson
- W. H. H. Clayton, American soldier, lawyer, judge in post-Civil War Arkansas and Indian Territory Oklahoma
- William L. Clayton, US assistant secretary of state for economic affairs
- William Clayton (colonist), acting Governor of the Pennsylvania Colony, 1684–1685
- William Wirt Clayton, judge, director and tax collector in Atlanta, Georgia
- William M. Clayton, US politician, mayor of Denver, Colorado, 1868–1869
Other
- William Clayton (Mormon), Mormon pioneer
- William Clayton (architect), prominent New Zealand architect
- William Clayton (publisher), publisher of Astounding Stories
- William Cecil Clayton, a character in Edgar Rice Burroughs's Tarzan novels
- William Clayton (Arrowverse), a character in the TV series Arrow
- William Clinton Clayton Jr., American courier driver and murder victim