William Brandon
William Brandon may refer to:
- William Brandon (died 1491), English knight
- William Brandon (standard-bearer), supporter of Henry VII of England's conquest and father of Charles Brandon, 1st Duke of Suffolk, son of the above
- William Brandon (author), American writer and historian
- William Brandon (Wisconsin politician), Wisconsin State Assemblyman
- William L. Brandon, Confederate officer
- William W. Brandon, former Governor of Alabama
- William Brandon (musician), alternative rock musician who played with Ocha la Rocha
- William Brandon (MP), Member of Parliament for New Shoreham
- Will Brandon, character in ''All for Peggy''