Wilkes
- Battery Wilkes
- Clarie Coast
- John Wilkes
- Wake Island
- Wilk
- Wilken
- Wilkens
- Wilkes (horse)
- Wilkes (surname)
- Wilkes Angel
- Wilkes Basin
- Wilkes C. Robinson
- Wilkes Community College
- Wilkes County, Georgia
- Wilkes County, North Carolina
- Wilkes Honors College
- Wilkes Island
- Wilkes Land
- Wilkes Power Plant
- Wilkes Station
- Wilkes University
- Wilkes, Portland, Oregon
- Wilkes-Barre Township, Luzerne County, Pennsylvania
- Wilkes-Barre Variation
- Wilkes-Barre, Pennsylvania
- Wilks (disambiguation)