WISE
- WISE (AM)
- WISE Campaign
- WISE Installation System
- WISE-FM
- WISE-TV
- Web-based Inquiry Science Environment
- West Ipoh Span Expressway
- Wide-field Infrared Survey Explorer
- Wilberforce Institute for the study of Slavery and Emancipation
- Wind Science and Engineering Research Center
- Windows Interface Source Environment
- Wing-in-surface-effect
- Wise (disambiguation)
- Women's Islamic Initiative in Spirituality and Equality
- Work improvement in small enterprises
- World Information Service on Energy
- World Innovation Summit for Education
- World Institute of Scientology Enterprises
- World Islamic Sciences and Education University