SR 182 begins at an intersection with US 13 in the town of Painter. The state highway follows two-lane undivided Main Street very briefly east of US 13, during which the highway intersects an inactiverailroad line. East of the inactive rail line, SR 182turns north onto Railroad Avenue, then veers east onto Edmunds Street. The state highway leaves town along Mappsburg Road, which the highway follows to the hamlet of Mappsburg. SR 182 continues east as Quinby Bridge Road, which crosses the Machipongo River on the namesake bridge. The state highway reaches its eastern terminus at SR 605, which heads north as Bradfords Neck Road and south as Upshur Neck Road through the village of Quinby on Upshur Bay.