Verocay body
Verocay bodies were first described by Uruguayan neuro-pathologist in 1910. It is a required histopathological finding for diagnosing schwannomas.
Verocay bodies are a component of "Antoni A" which are the dense areas of schwannomas located between palisading Von [Economo neuron|spindle cell]s found in neoplasms. Two nuclear palisading regions and an anuclear zone make up one Verocay body.
Originally Verocay bodies were called 'neuromas', a term coined by Louis Odier in 1803. The name changed to ‘neuro-fibroma’ under Friedrich [Daniel von Recklinghausen|Von Recklinghausen] and later in 1935 to ‘neurilemmomas’ under Arthur Purdy Stout. When Harkin and Reed coined the term 'schwannoma' in 1968, Verocay bodies received their present-day name.
Features on histopathological examination include:
1. Eosinophilic acellular area due to overexpression of lamins.
2. Consisting of reduplicated basement membrane and cytoplasmic processes.