Uptown
- Albuquerque, New Mexico
- Buckhead
- Cityscape of Cincinnati
- Downtown (disambiguation)
- Golden Square Mile
- Hochhaus Uptown München
- Midtown (disambiguation)
- New Westminster, British Columbia
- Port Alberni, British Columbia
- Roy Orbison
- SM City CDO Uptown
- Saint John, New Brunswick
- So Far Gone (mixtape)
- Uptown (1987 film)
- Uptown (2009 film)
- Uptown (André Previn album)
- Uptown (Billy Taylor album)
- Uptown (Machinations album)
- Uptown (Prince song)
- Uptown (The Crystals song)
- Uptown (band)
- Uptown (newspaper)
- Uptown Charlotte
- Uptown Funk
- Uptown Girl
- Uptown Houston
- Uptown Kingston, New York
- Uptown Lexington
- Uptown Manhattan
- Uptown New Orleans
- Uptown Oakland
- Uptown Pittsburgh
- Uptown Records
- Uptown Records (jazz)
- Uptown Tampa
- Uptown Theatre (disambiguation)
- Uptown Toronto
- Uptown, Brisbane
- Uptown, Chicago
- Uptown, Dallas
- Uptown, Harrisburg
- Uptown, Hartford
- Uptown, Memphis
- Uptown, Minneapolis
- Uptown, New Orleans
- Uptown, Richmond
- Uptown, Seattle, Washington
- Uptown, Wichita, Kansas
- Victoria, British Columbia
- Waterloo, Ontario