USU
- Amarna Letters
- Francisco B. Reyes Airport
- Mount Usu
- Tyre, Lebanon
- USU (operating system)
- USU Software
- Ulyanovsk State University
- Uniformed Services University
- United States University
- Universal Student Unionism
- Universidade Santa Úrsula
- University of North Sumatra
- University of Sydney Union
- Unseptunium
- Ural State University
- Ushu
- Usu (mortar)
- Utah State University
- Uttarakhand Sanskrit University
- Wusu