USP
- John Hope Franklin Center for Interdisciplinary and International Studies
- USP (Victoria)
- Ultra-short period planets
- Ultrashort pulse laser
- Ultraspiracle protein
- Unified settlement planning
- Unified shader model
- Unique selling proposition
- United States Penitentiary
- United States Pharmacopeia
- United States patent
- Unité Spéciale de la Police
- Universal Storage Platform
- Universal stress protein
- University of Southeastern Philippines
- University of Southern Philippines Foundation
- University of São Paulo
- University of the Sciences in Philadelphia
- University of the South Pacific
- Urs Samyuktha Paksha
- Useful space principle
- Uspantek language
- Utah State Prison
- Utrecht Science Park
- Uttama Seva Padakkama