UMC
- Ljubljana University Medical Centre
- Seven (Bob Seger album)
- Sharp Corporation
- Texas Tech University Health Sciences Center
- The U.M.C.'s
- UMC (computer)
- USB mass storage device class
- Ukrainian Mobile Communications
- Uniform Mechanical Code
- Union Metallic Cartridge Company
- United Medical Center
- United Methodist Church
- United Microelectronics Corporation
- Universal Mind Control
- Universidade de Mogi das Cruzes
- University Medical Center (Tucson, Arizona)
- University Medical Center Utrecht
- University Medical Center of Southern Nevada
- University of Colorado Boulder
- University of Minnesota Crookston
- University of Mississippi Medical Center
- Uppsala Monitoring Centre
- Urban Movie Channel