UH-232

UH-232 is a drug which acts as a subtype selective mixed agonist-antagonist for dopamine receptors, acting as a weak partial agonist at the D₃ subtype, and an antagonist at D₂Sh autoreceptors on dopaminergic nerve terminals. It causes dopamine release in the brain and has a stimulant effect, as well as blocking the behavioural effects of cocaine. It may also serve as a 5-HT_2A receptor agonist, based on animal studies.
It was investigated in clinical trials for the treatment of schizophrenia, but unexpectedly caused symptoms to become worse.

(+)-AJ76

The N-monopropyl derivative -AJ76 is an active metabolite of UH-232 and has practically identical effects.
Image:-AJ76 structure.svg|200px|thumb|left|class=skin-invert-image|-AJ76, CAS# 85378-82-1,