Triphenyliodoethylene


Triphenyliodoethylene, also known as iodotriphenylethylene or as phenylstilbene iodide, as well as triphenylvinyl iodide, is a synthetic nonsteroidal estrogen of the triphenylethylene group that is related to triphenylchloroethylene and triphenylbromoethylene and was never marketed.

SAR

Although the effect of vinylic halogenation has already been discussed, it was discovered that Triphenylacrylonitrile also potently modulates the estrogen receptor. The synthesis of this agent is described in the pendant literature.