Transporter Classification Database

Classification

1. Channels">Ion channel">Channels and pores

1.A α-type channels

• 1.A.1 Voltage-gated ion channel superfamily
• 1.A.2 Inward-rectifier K⁺ channel family
• 1.A.3 Ryanodine-inositol-1,4,5-trisphosphate receptor Ca²⁺ channel family
• 1.A.4 Transient receptor potential Ca²⁺ channel family
• 1.A.5 Polycystin cation channel family
• 1.A.6 Epithelial Na⁺ channel family
• 1.A.7 ATP-gated P2X receptor cation channel family
• 1.A.8 Major intrinsic protein superfamily
• 1.A.9 Neurotransmitter receptor, Cys loop, ligand-gated ion channel family
• 1.A.10 Glutamate-gated ion channel family of neurotransmitter receptors
• 1.A.11 Ammonium channel transporter family
• 1.A.12 Intracellular chloride channel family
• 1.A.13 Epithelial chloride channel family
• 1.A.14 Testis-enhanced gene transfer family
• 1.A.15 Nonselective cation channel-2 family
• 1.A.16 Formate-nitrite transporter family
• 1.A.17 Calcium-dependent chloride channel family
• 1.A.18 Chloroplast envelope anion-channel-forming Tic110 family
• 1.A.19 Type A influenza virus matrix-2 channel family
• 1.A.20 BCL2/Adenovirus E1B-interacting protein 3 family
• 1.A.21 Bcl-2 family
• 1.A.22 Large-conductance mechanosensitive ion channel
• 1.A.23 Small-conductance mechanosensitive ion channel
• 1.A.24 Gap-junction-forming connexin family
• 1.A.25 Gap-junction-forming innexin family
• 1.A.26 Mg²⁺ transporter-E family
• 1.A.27 Phospholemman family
• 1.A.28 Urea transporter family
• 1.A.29 Urea/amide channel family
• 1.A.30 H⁺- or Na⁺-translocating bacterial MotAB flagellar motor/ExbBD outer-membrane transport energizer superfamily
• 1.A.31 Annexin family
• 1.A.32 Type B influenza virus NB channel family
• 1.A.33 Cation-channel-forming heat shock protein 70 family
• 1.A.34 Bacillus gap junction-like channel-forming complex family
• 1.A.35 CorA metal ion transporter family
• 1.A.36 Intracellular chloride channel family
• 1.A.37 CD20 Ca²⁺ channel family
• 1.A.38 Golgi pH regulator family
• 1.A.39 Type C influenza virus CM2 channel family
• 1.A.40 Human immunodeficiency virus type I Vpu channel family
• 1.A.41 Avian reovirus p10 Vvroporin family
• 1.A.42 HIV viral protein R family
• 1.A.43 Camphor resistance or fluoride exporter family
• 1.A.44 Pore-forming tail Tip pb2 protein of phage T5 family
• 1.A.45 Phage P22 injectisome family
• 1.A.46 Anion channel-forming bestrophin family
• 1.A.47 Nucleotide-sensitive anion-selective channel, ICln family
• 1.A.48 Anion channel Tweety family
• 1.A.49 Human coronavirus ns12.9 viroporin family
• 1.A.50 Phospholamban (Ca²⁺-channel and Ca²⁺-ATPase regulator) family
• 1.A.51 The Voltage-gated Proton Channel Family
• 1.A.52 The Ca²⁺ Release-activated Ca²⁺ Channel Family
• 1.A.53 The Hepatitis C Virus P7 Viroporin Cation-selective Channel Family
• 1.A.54 The Presenilin ER Ca²⁺ Leak Channel Family
• 1.A.55 The Synaptic Vesicle-Associated Ca²⁺ Channel, Flower Family
• 1.A.56 The Copper Transporter Family
• 1.A.57 The Human SARS Coronavirus Viroporin
• 1.A.58 The Type B Influenza Virus Matrix Protein 2 Family
• 1.A.59 The Bursal Disease Virus Pore-Forming Peptide, Pep46 Family
• 1.A.60 The Mammalian Reovirus Pre-forming Peptide, Mu-1 Family
• 1.A.61 The Insect Nodavirus Channel-forming Chain F Family
• 1.A.62 The Homotrimeric Cation Channel Family
• 1.A.63 The Ignicoccus Outer Membrane α-helical Porin Family
• 1.A.65 The Coronavirus Viroporin E Protein Family
• 1.A.66 The Pardaxin Family
• 1.A.67 The Membrane Mg²⁺ Transporter Family
• 1.A.68 The Viral Small Hydrophobic Viroporin Family
• 1.A.69 The Heteromeric Odorant Receptor Channel Family
• 1.A.70 The Molecule Against Microbes A Family
• 1.A.71 The Brain Acid-soluble Protein Channel Family
• 1.A.72 The Mer Superfamily
• 1.A.73 The Colicin Lysis Protein Family
• 1.A.74 The Mitsugumin 23 Family
• 1.A.75 The Mechanical Nociceptor, Piezo Family
• 1.A.76 The Magnesium Transporter1 Family
• 1.A.77 The Mg²⁺/Ca²⁺ Uniporter Family
• 1.A.78 The K⁺-selective Channel in Endosomes and Lysosomes Family
• 1.A.79 The Cholesterol Uptake Protein or Double Stranded RNA Uptake Family
• 1.A.80 The NS4a Viroporin Family
• 1.A.81 The Low Affinity Ca²⁺ Channel Family
• 1.A.82 The Hair Cell Mechanotransduction Channel Family
• 1.A.83 The SV40 Virus Viroporin VP2 Family
• 1.A.84 The Calcium Homeostasis Modulator Ca²⁺ Channel Family
• 1.A.85 The Poliovirus 2B Viroporin Family
• 1.A.86 The Human Papilloma Virus type 16 L2 Viroporin Family
• 1.A.87 The Mechanosensitive Calcium Channel Family
• 1.A.88 The Fungal Potassium Channel Family
• 1.A.89 The Human Coronavirus 229E Viroporin Family
• 1.A.90 The Human Metapneumovirus Viroporin Family
• 1.A.91 The Cytoadherence-linked Asexual Protein 3.2 of Plasmodium falciparum Family
• 1.A.92 The Reovirus Viroporin VP10 Family
• 1.A.93 The Bluetongue Virus Non-Structural Protein 3 Viroporin Family
• 1.A.94 The Rotavirus Non-structural Glycoprotein 4 Viroporin Family
• 1.A.95 The Ephemerovirus Viroporin Family
• 1.A.96 The Human Polyoma Virus Viroporin Family
• 1.A.97 The Human Papillomavirus type 16 E5 Viroporin Family
• 1.A.98 Human T-Lymphotropic Virus 1 P13 protein Family
• 1.A.99 The Infectious Bronchitis Virus Envelope Small Membrane Protein E Family
• 1.A.100 The Rhabdoviridae Putative Viroporin, U5 Family
• 1.A.101 The Peroxisomal Pore-forming Pex11 Family
• 1.A.102 Influenza A viroporin PB1-F2 Family
• 1.A.103 The Simian Virus 5 SH Family
• 1.A.104 The Proposed Flagellar Biosynthesis Na⁺ Channel, FlaH Family
• 1.A.105 The Mixed Lineage Kinase Domain-like Family
• 1.A.106 The Calcium Load-activated Calcium Channel Family
• 1.A.107 The Pore-forming Globin Family

1.B. β-Barrel porins">Porin (protein)">β-Barrel porins and other outer membrane proteins

• 1.B.1 General bacterial porin family
• 1.B.2 Chlamydial porin family
• 1.B.3 Sugar porin family
• 1.B.4 Brucella-Rhizobium porin family
• 1.B.5 Pseudomonas OprP porin family
• 1.B.6 OmpA-OmpF porin (OOP) family
• 1.B.7 Rhodobacter PorCa porin family
• 1.B.8 Mitochondrial and plastid porin (MPP) family
• 1.B.9 FadL outer membrane protein (FadL) family
• 1.B.10 Nucleoside-specific channel-forming outer membrane porin (Tsx) family
• 1.B.11 Outer membrane fimbrial usher porin family
• 1.B.12 Autotransporter-1 family
• 1.B.13 Alginate export porin family
• 1.B.14 Outer membrane receptor (OMR) family
• 1.B.15 Raffinose porin family
• 1.B.16 Short chain amide and urea porin family
• 1.B.17 Outer membrane factor (OMF) family
• 1.B.18 Outer membrane auxiliary (OMA) protein family
• 1.B.19 Glucose-selective OprB porin family
• 1.B.20 Two-partner secretion family
• 1.B.21 OmpG porin (OmpG) family
• 1.B.22 Outer bacterial membrane secretin family
• 1.B.23 Cyanobacterial porin family
• 1.B.24 Mycobacterial porin
• 1.B.25 Outer membrane porin (Opr) family
• 1.B.26 Cyclodextrin porin family
• 1.B.31 Campylobacter jejuni major outer membrane porin family
• 1.B.32 Fusobacterial outer membrane porin family
• 1.B.33 Outer membrane protein insertion porin family
• 1.B.34 Corynebacterial porins
• 1.B.35 Oligogalacturonate-specific porin (KdgM) family
• 1.B.39 Bacterial porin, OmpW (OmpW) family
• 1.B.42 Outer membrane lipopolysaccharide export porin family
• 1.B.43 Coxiella porin P1 family
• 1.B.44 Probable protein translocating porphyromonas gingivalis porin family
• 1.B.49 Anaplasma P44 porin family
• 1.B.48 Curli-like transporters
• 1.B.54 Intimin/Invasin or Autotransporter-3 family
• 1.B.55 Poly-acetyl-D-glucosamine porin family
• 1.B.57 Legionella major-outer membrane protein family
• 1.B.60 Omp50 porin family
• 1.B.61 Delta-proteobacterial porin family
• 1.B.62 Putative bacterial porin family
• 1.B.66 Putative beta-barrel porin-2 family
• 1.B.67 Putative beta barrel porin-4 family
• 1.B.68 Putative beta barrel porin-5 superfamily
• 1.B.70 Outer membrane channel family
• 1.B.71 Proteobacterial/verrucomicrobial porin family
• 1.B.72 Protochlamydial outer membrane porin family
• 1.B.73 Capsule biogenesis/assembly family
• 1.B.78 DUF3374 electron transport-associated porin family

1.C [Pore-forming toxin]s (proteins and peptides)

• 1.C.3 α-Hemolysin family
• 1.C.4 Aerolysin family
• 1.C.5 ε-toxin family
• 1.C.11 RTX-toxin superfamily
• 1.C.12 Membrane attack complex/perforin superfamily
• 1.C.13 Leukocidin family
• 1.C.14 Cytohemolysin family
• 1.C.39 Thiol-activated cholesterol-dependent cytolysin family
• 1.C.43 Lysenin family
• 1.C.56 Pseudomonas syringae HrpZ cation channel family
• 1.C.57 Clostridial cytotoxin family
• 1.C.58 The Microcin E492/C24 (Microcin E492) Family
• 1.C.74 Snake cytotoxin family
• 1.C.97 Pleurotolysin pore-forming family

1.D Non-ribosomally synthesized channels

• 1.D.1 The Gramicidin A Channel Family
• 1.D.2 The Channel-forming Syringomycin Family
• 1.D.3 The Channel-Forming Syringopeptin Family
• 1.D.4 The Tolaasin Channel-forming Family
• 1.D.5 The Alamethicin or Peptaibol Antibiotic Channel-forming Family
• 1.D.6 The Complexed Poly 3-Hydroxybutyrate Ca²⁺ Channel Family
• 1.D.7 The Beticolin Family
• 1.D.8 The Saponin Family
• 1.D.9 The Polyglutamine Ion Channel Family
• 1.D.10 The Ceramide-forming Channel Family
• 1.D.11 The Surfactin Family
• 1.D.12 The Beauvericin Family
• 1.D.13 DNA-delivery Amphipathic Peptide Antibiotics
• 1.D.14 The Synthetic Leu/Ser Amphipathic Channel-forming Peptide Family
• 1.D.15 The Daptomycin (Daptomycin) Family
• 1.D.16 The Synthetic Amphipathic Pore-forming Heptapeptide Family
• 1.D.17 Combinatorially-designed, Pore-forming, β-sheet Peptide Family
• 1.D.18 The Pore-forming Guanosine-Bile Acid Conjugate Family
• 1.D.19 Ca²⁺ Channel-forming Drug, Digitoxin Family
• 1.D.20 The Pore-forming Polyene Macrolide Antibiotic/fungal Agent Family
• 1.D.21 The Lipid Nanopore Family
• 1.D.22 The Proton-Translocating Carotenoid Pigment, Zeaxanthin Family
• 1.D.23 Phenylene Ethynylene Pore-forming Antimicrobial Family
• 1.D.24 The Marine Sponge Polytheonamide B Family
• 1.D.25 The Arylamine Foldamer Family
• 1.D.26 The Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside Family
• 1.D.27 The Thiourea isosteres Family
• 1.D.28 The Lipopeptaibol Family
• 1.D.29 The Macrocyclic Oligocholate Family
• 1.D.30 The Artificial Hydrazide-appended pillararene Channels Family
• 1.D.31 The Amphotericin B Family
• 1.D.32 The Pore-forming Novicidin Family
• 1.D.33 The Channel-forming Polytheonamide B Family
• 1.D.34 The Channel-forming Oligoester Bolaamphiphiles
• 1.D.35 The Pore-forming cyclic Lipodepsipeptide Family
• 1.D.36 The Oligobornene Ion Channel Family
• 1.D.37 The Hibicuslide C Family
• 1.D.38 The Cyclic Peptide Nanotube Family
• 1.D.39 The Light-controlled Azobenzene-based Amphiphilic Molecular Ion Channel Family
• 1.D.40 The Protein-induced Lipid Toroidal Pore Family
• 1.D.41 The Sprotetonate-type Ionophore Family
• 1.D.42 The Phe-Arg Tripeptide-PillarArene Channel Family
• 1.D.43 The Triazole-tailored Guanosine Dinucleoside Channel Family
• 1.D.44 The Synthetic Ion Channel with Redox-active Ferrocene Family
• 1.D.45 The Sonoporation and Electroporation Membrane Pore Family
• 1.D.46 The DNA Nanopore Family
• 1.D.47 The Pore-forming Synthetic Cyclic Peptide Family
• 1.D.48 The Pore-forming Syringomycin E Family
• 1.D.49 The Transmembrane Carotenoid Radical Channel Family
• 1.D.50 The Amphiphilic bis-Catechol Anion Transporter Family
• 1.D.51 The Protein Nanopore Family
• 1.D.52 The Aromatic Oligoamide Macrocycle Nanopore Family
• 1.D.53 The alpha, gamma-Peptide Nanotube Family
• 1.D.54 The potassium-selective Hexyl-Benzoureido-15-Crown-5-Ether Ion Channel Family
• 1.D.55 The Porphyrin-based Nanopore Family
• 1.D.56 The Alpha-Aminoisobutyrate Oligomeric Nanopore Family
• 1.D.57 The Lipid Electro-Pore Family
• 1.D.58 The Anion Transporting Prodigiosene Family
• 1.D.59 The Anion Transporting Perenosin Family
• 1.D.60 The Alpha,Gamma-Cyclic Peptide Family
• 1.D.61 The Anionophoric Family
• 1.D.62 The Bis-Triazolyl DiGuanosine Derivative Channel-forming Family
• 1.D.63 The Peptide-based Nanopore Family
• 1.D.64 The Carbon Nanotube Family
• 1.D.65 The Pore-forming Amphidinol Family
• 1.D.66 The Helical Macromolecule Nanopore Family
• 1.D.67 The Crown Ether-modified Helical Peptide Ion Channel Family
• 1.D.68 The Pore-forming Pleuronic Block Polymer Family
• 1.D.69 The Conical Nanopore Family
• 1.D.70 The Metallic Nanopore Family
• 1.D.71 The Synthetic TP359 Peptide Family
• 1.D.72 The Chloride Carrier Triazine-based Tripodal Receptor Family
• 1.D.73 The Mesoporous Silica Nanopore Family
• 1.D.74 The Stimulus-responsive Synthetic Rigid p-Octiphenyl Stave Pore Family

1.F [Vesicle fusion] pores

• 1.F.1 The Synaptosomal Vesicle Fusion Pore Family
• 1.F.2 The Octameric Exocyst Family

1.G Viral fusion">Viral protein#Viral envelope">Viral fusion pores

• 1.G.1 The Viral Pore-forming Membrane Fusion Protein-1 Family
• 1.G.2 The Viral Pore-forming Membrane Fusion Protein-2 Family
• 1.G.3 The Viral Pore-forming Membrane Fusion Protein-3 Family
• 1.G.4 The Viral Pore-forming Membrane Fusion Protein-4 Family
• 1.G.5 The Viral Pore-forming Membrane Fusion Protein-5 Family
• 1.G.6 The Hepadnaviral S Fusion Protein Family
• 1.G.7 The Reovirus FAST Fusion Protein Family
• 1.G.8 The Arenavirus Fusion Protein Family
• 1.G.9 The Syncytin Family
• 1.G.10 The Herpes Simplex Virus Membrane Fusion Complex Family
• 1.G.11 Poxvirus Cell Entry Protein Complex Family
• 1.G.12 The Avian Leukosis Virus gp95 Fusion Protein Family
• 1.G.13 The Orthoreovirus Fusion-associated Small Transmembrane Family
• 1.G.14 The Influenza Virus Hemagglutinin/Fusion Pore-forming Protein Family
• 1.G.15 The Autographa californica Nuclear Polyhedrosis Virus Major Envelope Glycoprotein GP64 Family
• 1.G.16 The Human Immunodeficiency Virus Type 1 Fusion Peptide Family
• 1.G.17 The Bovine Leukemia Virus Envelop Glycoprotein Family
• 1.G.18 The SARS-CoV Fusion Peptide in the Spike Glycoprotein Precursor Family
• 1.G.19 The Rotavirus Pore-forming Membrane Fusion Complex Family
• 1.G.20 The Hantavirus Gc Envelope Fusion Glycoprotein Family
• 1.G.21 The Epstein Barr Virus Gp42 Family
• 1.G.22 The Cytomegalovirus Glycoprotein gO Family

1.H [Paracellular channel]s

• 1.H.1 The Claudin Tight Junction Family
• 1.H.2 The Invertebrate PMP22-Claudin Family

1.I [Membrane-bound channel]s

• 1.I.1 Nuclear pore complex family, including karyopherins
• 1.I.2 Plant plasmodesmata family

2. Electrochemical potential-driven transporters

2.A Porters ([uniporter]s, [symporter]s, [antiporter]s)

• 2.A.1 Major Facilitator superfamily, see also Lactose permease, Phosphate permease and Glucose transporter
• 2.A.2 The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family
• 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
• 2.A.4 Cation diffusion facilitator Family
• 2.A.5 Zinc (Zn²⁺)-Iron (Fe²⁺) Permease Family
• 2.A.6 Resistance-Nodulation-Cell Division Superfamily, see also SecDF protein-export membrane protein
• 2.A.7 The Drug/Metabolite Transporter Superfamily
• 2.A.8 The Gluconate:H⁺ Symporter Family
• 2.A.9 The Membrane Protein Insertase Family
• 2.A.10 The 2-Keto-3-Deoxygluconate Transporter Family
• 2.A.11 The Citrate-Mg²⁺:H⁺ Citrate-Ca²⁺:H⁺ Symporter Family
• 2.A.12 ATP:ADP Antiporter Family
• 2.A.13 The C4-Dicarboxylate Uptake Family
• 2.A.14 Lactate Permease Family
• 2.A.15 The Betaine/Carnitine/Choline Transporter (BCCT) Family
• 2.A.16 Tellurite-resistance/Dicarboxylate Transporter Family
• 2.A.17 Proton-dependent Oligopeptide Transporter Family
• 2.A.18 The Amino Acid/Auxin Permease Family
• 2.A.19 The Ca²⁺:Cation Antiporter Family
• 2.A.20 The Inorganic Phosphate Transporter Family
• 2.A.21 Solute:Sodium Symporter Family
• 2.A.22 The Neurotransmitter:Sodium Symporter Family
• 2.A.23 The Dicarboxylate/Amino Acid:Cation Symporter Family
• 2.A.24 The 2-Hydroxycarboxylate Transporter Family
• 2.A.25 Alanine or Glycine:Cation Symporter Family
• 2.A.26 The Branched Chain Amino Acid:Cation Symporter Family
• 2.A.27 The Glutamate:Na⁺ Symporter Family
• 2.A.28 Bile Acid:Na⁺ Symporter Family
• 2.A.29 Mitochondrial carrier Family
• 2.A.30 Cation-Chloride Cotransporter Family
• 2.A.31 Anion Exchanger Family
• 2.A.32 The Silicon Transporter Family
• 2.A.33 NhaA Na⁺:H⁺ Antiporter Family
• 2.A.34 The NhaB Na⁺:H⁺ Antiporter Family
• 2.A.35 The NhaC Na⁺:H⁺ Antiporter Family
• 2.A.36 Monovalent Cation:Proton Antiporter-1 Family
• 2.A.37 Monovalent Cation:Proton Antiporter-2 Family
• 2.A.38 K⁺ Transporter (Trk) Family
• 2.A.39 Nucleobase:Cation Symporter-1 Family
• 2.A.40 Nucleobase:Cation Symporter-2 Family
• 2.A.41 The Concentrative Nucleoside Transporter Family
• 2.A.42 The Hydroxy/Aromatic Amino Acid Permease Family
• 2.A.43 The Lysosomal Cystine Transporter Family
• 2.A.45 Arsenite-Antimonite Efflux Family
• 2.A.46 The Benzoate:H⁺ Symporter Family
• 2.A.47 Divalent Anion:Na⁺ Symporter Family
• 2.A.48 The Reduced Folate Carrier Family
• 2.A.49 Chloride Carrier/Channel Family
• 2.A.50 The Glycerol Uptake Family
• 2.A.51 The Chromate Ion Transporter Family
• 2.A.52 The Ni²⁺-Co²⁺ Transporter Family
• 2.A.53 Sulfate permease Family
• 2.A.54 The Mitochondrial Tricarboxylate Carrier Family
• 2.A.55 The Metal Ion (Mn²⁺-iron) Transporter Family
• 2.A.56 The Tripartite ATP-independent Periplasmic Transporter Family
• 2.A.57 The Equilibrative Nucleoside Transporter Family
• 2.A.58 The Phosphate:Na⁺ Symporter Family
• 2.A.59 The Arsenical Resistance-3 Family
• 2.A.60 Organo Anion Transporter Family
• 2.A.61 The C4-dicarboxylate Uptake C Family
• 2.A.62 The NhaD Na⁺:H⁺ Antiporter Family
• 2.A.63 The Monovalent Cation (K⁺ or Na⁺):Proton Antiporter-3 Family
• 2.A.64 Twin Arginine Targeting (Tat) Family
• 2.A.65 The Bilirubin Transporter Family
• 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide Flippase Superfamily
• 2.A.67 The Oligopeptide Transporter Family
• 2.A.68 The p-Aminobenzoyl-glutamate Transporter Family
• 2.A.69 The Auxin Efflux Carrier Family
• 2.A.70 The Malonate:Na⁺ Symporter Family
• 2.A.71 The Folate-Biopterin Transporter Family
• 2.A.72 The K⁺ Uptake Permease Family
• 2.A.73 The Short Chain Fatty Acid Uptake Family
• 2.A.74 The 4 TMS Multidrug Endosomal Transporter Family
• 2.A.75 The L-Lysine Exporter Family
• 2.A.76 The Resistance to Homoserine/Threonine Family
• 2.A.77 The Cadmium Resistance Family
• 2.A.78 The Branched Chain Amino Acid Exporter Family
• 2.A.79 The Threonine/Serine Exporter Family
• 2.A.80 The Tricarboxylate Transporter Family
• 2.A.81 The Aspartate:Alanine Exchanger Family
• 2.A.82 The Organic Solute Transporter Family
• 2.A.83 The Na⁺-dependent Bicarbonate Transporter Family
• 2.A.84 The Chloroplast Maltose Exporter Family
• 2.A.85 The Aromatic Acid Exporter Family
• 2.A.86 The Autoinducer-2 Exporter Family
• 2.A.87 The Prokaryotic Riboflavin Transporter Family
• 2.A.88 Vitamin Uptake Transporter Family
• 2.A.89 The Vacuolar Iron Transporter Family
• 2.A.90 Vitamin A Receptor/Transporter Family
• 2.A.91 Mitochondrial tRNA Import Complex
• 2.A.92 The Choline Transporter-like Family
• 2.A.94 The Phosphate Permease Family
• 2.A.95 The 6TMS Neutral Amino Acid Transporter Family
• 2.A.96 The Acetate Uptake Transporter Family
• 2.A.97 The Mitochondrial Inner Membrane K⁺/H⁺ and Ca²⁺/H⁺ Exchanger Family
• 2.A.98 The Putative Sulfate Exporter Family
• 2.A.99 The 6TMS Ni²⁺ uptake transporter Family
• 2.A.100 The Ferroportin Family
• 2.A.101 The Malonate Uptake Family
• 2.A.102 The 4-Toluene Sulfonate Uptake Permease Family
• 2.A.103 The Bacterial Murein Precursor Exporter Family
• 2.A.104 The L-Alanine Exporter Family
• 2.A.105 The Mitochondrial Pyruvate Carrier Family
• 2.A.106 The Ca²⁺:H⁺ Antiporter-2 Family
• 2.A.107 The MntP Mn²⁺ Exporter Family
• 2.A.108 The Iron/Lead Transporter Family
• 2.A.109 The Tellurium Ion Resistance Family
• 2.A.110 The Heme Transporter, heme-responsive gene protein Family
• 2.A.111 The Na⁺/H⁺ Antiporter-E Family
• 2.A.112 The KX Blood-group Antigen Family
• 2.A.113 The Nickel/cobalt Transporter Family
• 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA Family
• 2.A.115 The Novobiocin Exporter Family
• 2.A.116 The Peptidoglycolipid Addressing Protein Family
• 2.A.117 The Chlorhexadine Exporter family
• 2.A.118 The Basic Amino Acid Antiporter Family
• 2.A.119 The Organo-Arsenical Exporter Family
• 2.A.120 The Putative Amino Acid Permease Family
• 2.A.121 The Sulfate Transporter Family
• 2.A.122 The LrgB/CidB holin-like auxiliary protein Family
• 2.A.123 The Sweet; PQ-loop; Saliva; MtN3 Family
• 2.A.124 The Lysine Exporter Family
• 2.A.125 The Eukaryotic Riboflavin Transporter Family
• 2.A.126 The Fatty Acid Exporter Family
• 2.A.127 Enterobacterial Cardiolipin Transporter Family

2.B Nonribosomally synthesized porters

• 2.B.1 The Valinomycin Carrier Family
• 2.B.2 The Monensin Family
• 2.B.3 The Nigericin Family
• 2.B.4 The Macrotetrolide Antibiotic Family
• 2.B.5 The Macrocyclic Polyether Family
• 2.B.6 The Ionomycin Family
• 2.B.7 The Transmembrane α-helical Peptide Phospholipid Translocation Family
• 2.B.8 The Bafilomycin A1 Family
• 2.B.9 The Cell Penetrating Peptide Functional Family
• 2.B.10 The Synthetic CPP, Transportan Family
• 2.B.11 The Calcimycin or A23187 Carrier-type Ionophore Family
• 2.B.12 The Salinomycin Family
• 2.B.13 The Tetrapyrrolic Macrocyclic Anion Antiporter Family
• 2.B.14 The Lasalocid A or X-537A Ionophore Family
• 2.B.15 The Tris-thiourea Tripodal-based Chloride Carrier Family
• 2.B.16 The Halogen-bond-containing Compound Anion Carrier Family
• 2.B.17 The Isophthalaminde Derivative H⁺:Cl⁻ Co-transporter Family
• 2.B.18 The Pyridine-2,6-Dicarboxamine Derivative H+:Cl⁻ Co-transporter Family
• 2.B.19 The Calixpyrrole Derivative Family
• 2.B.20 The Prodigiosin Chloride/Bicarbonate Exchanger Family
• 2.B.21 The ortho-Phenylenediamine-bis-Urea Derivative Anion Transporter Family
• 2.B.22 The Imidazolium-functionalized Anion Transporter Family
• 2.B.23 The Homotetrameric Transmembrane Zn²⁺/Co²⁺:Proton Synthetic Antiporter, Rocker Family
• 2.B.24 The Anion Carrier Family
• 2.B.25 The Peptide-mediated Lipid Flip-Flop Family
• 2.B.26 The Conjugate Family
• 2.B.27 The Tris-Urea Anion Transporter Family
• 2.B.29 The Anionophoric Marine Alkaloid Tambjamine Family

2.C Ion-gradient-driven energizers

• 2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR Family of Auxiliary Proteins for Energization of Outer Membrane Receptor -mediated Active Transport

3. [Primary active transport]ers

3.A. P-P-bond hydrolysis-driven transporters

• 3.A.1 ABC transporters including BtuCD, molybdate uptake transporter, Cystic fibrosis transmembrane conductance regulator and others
• 3.A.2 The H⁺- or Na⁺-translocating F-type ATPase, V-type ATPase and A-type ATPase superfamily
• 3.A.3 The P-type ATPase Superfamily
• 3.A.4 The Arsenite-Antimonite efflux family
• 3.A.5 General secretory pathway translocon
• 3.A.6 The Type III Secretory Pathway Family
• 3.A.7 The Type IV Secretory Pathway Family
• 3.A.8 The Mitochondrial Protein Translocase Family
• 3.A.9 The Chloroplast Envelope Protein Translocase Family
• 3.A.10 H⁺, Na⁺-translocating Pyrophosphatase family
• 3.A.11 The Bacterial Competence-related DNA Transformation Transporter Family
• 3.A.12 The Septal DNA Translocator Family
• 3.A.13 The Filamentous Phage Exporter Family
• 3.A.14 The Fimbrilin/Protein Exporter Family
• 3.A.15 The Outer Membrane Protein Secreting Main Terminal Branch Family
• 3.A.16 The Endoplasmic Reticular Retrotranslocon Family
• 3.A.17 The Phage T7 Injectisome Family
• 3.A.18 The Nuclear mRNA Exporter Family
• 3.A.19 The TMS Recognition/Insertion Complex Family
• 3.A.20 The Peroxisomal Protein Importer Family
• 3.A.21 The C-terminal Tail-Anchored Membrane Protein Biogenesis/ Insertion Complex Family
• 3.A.22 The Transcription-coupled TREX/TAP Nuclear mRNA Export Complex Family
• 3.A.23 The Type VI Symbiosis/Virulence Secretory Pathway Family
• 3.A.24 Type VII or ESX Protein Secretion System Family
• 3.A.25 The Symbiont-specific ERAD-like Machinery Family
• 3.A.26 The Plasmodium Translocon of Exported proteins Family

3.B Decarboxylation-driven transporters

• 3.B.1 The Na⁺-transporting Carboxylic Acid Decarboxylase Family

3.C Methyltransfer-driven transporters

• 3.C.1 The Na⁺ Transporting Methyltetrahydromethanopterin:Coenzyme M Methyltransferase Family

3.D. Oxidoreduction-driven transporters

• 3.D.1 The H⁺ or Na⁺-translocating NADH Dehydrogenase family
• 3.D.2 The Proton-translocating Transhydrogenase Family
• 3.D.3 The Proton-translocating Quinol:Cytochrome c Reductase) Superfamily
• 3.D.4 Proton-translocating Cytochrome Oxidase Superfamily
• 3.D.5 The Na⁺-translocating NADH:Quinone Dehydrogenase Family
• 3.D.6 The Putative Ion -translocating NADH:Ferredoxin Oxidoreductase Family
• 3.D.7 The H₂:Heterodisulfide Oxidoreductase Family
• 3.D.8 The Na⁺- or H⁺-Pumping Formyl Methanofuran Dehydrogenase Family
• 3.D.9 The H⁺-translocating F420H2 Dehydrogenase Family
• 3.D.10 The Prokaryotic Succinate Dehydrogenase Family

3.E. Light absorption-driven transporters

• Bacteriorhodopsin-like proteins including rhodopsin
• Bacterial photosynthetic reaction centres and photosystems I and II
• Light harvesting complexes from bacteria and chloroplasts

4. Group translocators

4.A Phosphotransfer-driven group translocators

• 4.A.1 The PTS Glucose-Glucoside (Glc) Family
• 4.A.2 The PTS Fructose-Mannitol Family
• 4.A.3 The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside Family
• 4.A.4 The PTS Glucitol Family
• 4.A.5 The PTS Galactitol Family
• 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
• 4.A.7 The PTS L-Ascorbate Family

4.B Nicotinamide ribonucleoside uptake transporters

• 4.B.1 The Nicotinamide Ribonucleoside Uptake Permease Family

4.C Acyl CoA ligase-coupled transporters

• 4.C.1 The Proposed Fatty Acid Transporter Family
• 4.C.2 The Carnitine O-Acyl Transferase Family
• 4.C.3 The Acyl-CoA Thioesterase Family

4.D Polysaccharide Synthase/Exporters

• 4.D.1 The Putative Vectorial Glycosyl Polymerization Family
• 4.D.2 The Glycosyl Transferase 2 Family
• 4.D.3 The Glycan Glucosyl Transferase Family

4.E. Vacuolar Polyphosphate Polymerase-catalyzed Group Translocators

• 4.E.1 The Vacuolar Polyphosphate Polymerase Family

5. Transport electron carriers

5.A Transmembrane 2-electron transfer carriers

• 5.A.1 The Disulfide Bond Oxidoreductase D Family
• 5.A.2 The Disulfide Bond Oxidoreductase B Family
• 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase Family

5.B Transmembrane 1-electron transfer carriers

• 5.B.1 The Phagocyte NADPH Oxidase Family
• 5.B.2 The Eukaryotic Cytochrome b561 Family
• 5.B.3 The Geobacter Nanowire Electron Transfer Family
• 5.B.4 The Plant Photosystem I Supercomplex Family
• 5.B.5 The Extracellular Metal Oxido-Reductase Family
• 5.B.6 The Transmembrane Epithelial Antigen Protein-3 Ferric Reductase Family
• 5.B.7 The YedZ (YedZ) Family
• 5.B.8 The Trans-Outer Membrane Electron Transfer Porin/Cytochrome Complex Family
• 5.B.9 The Porin-Cytochrome c Family