Tinidazole

Tinidazole, sold under the brand name Tindamax among others, is a medication used against infections caused by certain anaerobic bacteria and protozoa. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class.
Tinidazole is a therapeutic alternative on the WHO Model [List of Essential Medicines|World Health Organization's List of Essential Medicines].

Medical uses

Tinidazole is a narrow spectrum antimicrobial drug used to treat infections caused by Helicobacter pylori, Entamoeba histolytica, Giardia spp. and Trichomonas vaginalis.

Side effects

Drinking alcohol while taking tinidazole causes an unpleasant disulfiram-like reaction, which includes nausea, vomiting, headache, increased blood pressure, flushing, and shortness of breath.

Pharmacology

Pharmacokinetics

Elimination half-life is 13.2 ± 1.4 hours. Plasma half-life is 12 to 14 hours.

History

Tinidazole was approved for medical treatment in the United States in 2004.