Brian Thompson

• Brian Thompson (businessman), UnitedHealthcare CEO killed in 2024
• Brian Thompson (actor), American screen actor

Sports

• Brian Thompson (footballer, [born 1938)], English goalkeeper and concert promoter
• Brian Thompson (footballer, born 1950), from North East England
• Brian Thompson (footballer, born 1952), midfielder in the English Midlands
• Brian Thompson (sailor), British yachtsman

Others

• Brian Thompson (politician), American politician in Rhode Island
• Brian B. Thompson, British screenwriter