Thomas Lyons

• Thomas Lyons (Medal of Honor), American Civil War sailor and Medal of Honor recipient
• Thomas Lyons (politician), Northern Irish politician
• Thomas G. Lyons, American Democratic Party politician from Chicago, Illinois
• Thomas William Lyons, bishop of the Roman Catholic Church in the United States
• Tom Lyons, English footballer
• Tommy Lyons, Irish Gaelic football manager
• Tommy Lyons (American football), former American football offensive lineman, now surgeon
• Thomas Lyons (British Army officer), British general