Thomas Humphrey

• Thomas Humphrey (cricketer), English cricketer
• Tom Humphrey (artist), Scottish-born Australian artist
• T. C. Humphrey, state legislator in Arkansas
• Thomas E. Humphrey, chief justice of the Maine Superior Court
• Thomas M. Humphrey, American economist
• Thomas Humphrey (MP), English politician
• Thomas Humphrey, a fictional character from the TV series ''Orange Is the New Black''