Thomas Chamberlayne
Thomas Chamberlayne may refer to:
- Sir Thomas Chamberlayne , English judge who served as Chief Justice of Chester
- Sir Thomas Chamberlayne, 1st Baronet, of Wickham, Oxfordshire supported the Royalist cause in the English Civil War. He was Sheriff of Oxfordshire in 1643
- Sir Thomas Chamberlayne, 2nd Baronet, one of few men to receive a renewal of the baronetcy from the Lord Protector Oliver Cromwell
- Thomas Chamberlayne , English cricketer and yachtsman
- Thomas Chamberlayne, Dean of Bristol, 1739–1757