Thiopropazate

Thiopropazate is a typical antipsychotic of the phenothiazine class. It is a prodrug to perphenazine.
Thiopropazate is manufactured by Searle & Boehringer Mannheim
Thiopropazate is sold by Chembase, AAA Chemistry, ZINC, AKos Consulting & Solutions, Boc Sciences, ChemFrog, and ChemMol

Synthesis

The alkylation of 2-chloro-10-phenothiazine with Piperazine gives N-Desmethylprochlorperazine . Further alkylation with 2-Bromoethyl acetate gives Thiopropazate.