Tenilapine
Tenilapine is an atypical antipsychotic which has never been marketed in the US.
Pharmacodynamics
Tenilapine has a relatively high affinity for the 5-HT2A receptor, and relatively low affinities for dopamine receptors.| Receptor | Ki |
| dopamine [receptor D2|D2] | 1584 |
| D4 | 721±300 |
| 5-HT2A | 40 |
The ratio of D2 to D4 bonding is similar to that of clozapine. Like many other atypical antipsychotics, it is a potent 5-HT2C antagonist.