2,3,4,5-Tetramethoxyamphetamine
Tetramethoxyamphetamine, or 2,3,4,5-tetramethoxyamphetamine, also known as 2-methoxy-TMA or 3-methoxy-TMA-2, is a drug of the phenethylamine and amphetamine families related to mescaline.
In Alexander Shulgin's book PiHKAL, the minimum dose is listed as 50mg, and the duration as unknown but has been said to be relatively long-lived. TeMA is said to produce a threshold, disinhibited intoxication, mydriasis, and a headache. It is said to be roughly 6times as potent as mescaline.
TeMA has been said to be the only amphetamine with more than three methoxy groups known to be hallucinogenic. However, subsequently, the psychedelic properties of TeMA were questioned. Limited data exists about its pharmacological properties, metabolism, and toxicity. It was first described in the scientific literature by at least 1975. The drug is a controlled substance in Canada under phenethylamine blanket-ban language.