TSUP family


The 4-Toluene Sulfonate Uptake Permease family is also referred to as the TauE/SafE/YfcA/DUF81 Family.
Although its members have not been rigorously characterized, evidence is available that at least some members function in the transport of Sulfur containing Organic compounds. These include 4-toluene sulfonate which may be transported by the TsaS of Cupriavidus necator, sulfolactate which may be exported by the TauE protein of Cupriavidus necator and sulfoacetate which may be exported by the SafE1 protein of Neptuniibacter caesariensis. Another member of the TSUP family, TsaS of Comamonas testosteroni, has been reported to function in the uptake of 4-toluene sulfonate. None of these functional assignments can be considered to be certain.