TSC
- Air Transat
- Connected Places Catapult
- FK TSC
- TV Setouchi
- Taiwan Semiconductor Company Limited
- Tallahassee State College
- Teacher-Student Centre, University of Dhaka
- Teachers Service Commission
- Tech Support Comedy
- Technical Systems Consultants
- Technology Service Corporation
- Temporary Slavery Commission
- Ten Silver Coins
- Teridian Semiconductor
- Terminal Services Client
- Terrorist Screening Center
- Texas Southmost College
- Texas State Cemetery
- The Scots College
- The Secret Circle (TV series)
- The Shopping Channel
- The Soufan Center
- The Spaceship Company
- The Standard Code of Parliamentary Procedure
- The Support Center
- Thebarton Senior College
- Thiazide-sensitive Na-Cl cotransporter
- Thyristor switched capacitor
- Time Stamp Counter
- Time to Succeed Coalition
- Total Sanitation Campaign
- Tractor Supply Company
- Training Ship Chanakya
- Trans sodium crocetinate
- Trinidad State College
- Tuberous sclerosis complex
- Tuberous sclerosis protein
- Turkvision Song Contest