TPD52L2


Tumor protein D54 is a protein that in humans is encoded by the TPD52L2 gene.

Interactions

TPD52L2 has been shown to interact with TPD52L1 and TPD52.

Cellular function

TPD52L2 has a role in membrane traffic. TPD52L2 is found on small transport vesicles, termed intracellular nanovesicles, that transfer proteins between different cellular compartments. When TPD52L2 is depleted from HeLa cells, the following trafficking pathways are impaired: anterograde traffic, recycling of cargo and Golgi integrity. Proteomic analysis indicates that TPD52L2 is one of the most abundant proteins expressed in HeLa cells.