TMEM51

Transmembrane protein 51 is a protein in humans that is encoded by the TMEM51 gene. It is located on the first chromosome and has 6 isoforms in humans. It has orthologs in mammals, birds, reptiles, amphibians, and fish.
It is predicted to be a transmembrane protein due to the transmembrane regions within its coding sequence.
TMEM51-AS1 acts as a tumor suppressor when overexpressed, inhibiting cancer cell progression. Mutations or polymorphisms of the TMEM51 are associated susceptibility to Reynaud's syndrome.