TCIM

TCIM is a protein that in humans is encoded by the TCIM gene.

Function

This gene encodes a small, monomeric, predominantly unstructured protein. It is a positive regulator of the Wnt / beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes.