Stress dose
Perioperative stress doses of steroids to mitigate this rare but potentially fatal complications of perioperative use of steroid such as full-blown adrenal crisis in the perioperative period due to the secondary adrenal insufficiency. Various exogenous steroid preparations are used for a wide range of indications.
Stress doses
Emergency corticosteroid supplementation in patients taking exogenous corticosteroids:| Category | Initial | Subsequent |
| Minor procedure or surgery under local anesthesia | No extra supplementation is necessary | Continue normal dosing |
| Moderate surgical stress | 50 mg hydrocortisone IV | 25 mg of hydrocortisone every eight hours for 24 hours. Resume usual dose thereafter. |
| Major surgical stress | 100 mg hydrocortisone IV | 50 mg every eight hours for 24 hours. Taper dose by half per day to maintenance level. |
Pediatric doses
Emergent intramuscular dosing can be given if child is not tolerating oral medications or unable to get IV within 15 minutes. IM hydrocortisone sodium succinate doses are:- 25 mg for child 3 years and younger
- 50 mg for children >3 yrs – 12 years
- 100 mg for children 12 years and older.