List of highways numbered 141
- Alabama State Route 141
- Arkansas Highway 141
- California State Route 141
- Colorado State Highway 141
- County Road 141 (Hamilton County, Florida)
- County Road 141 (Madison County, Florida)
- County Route 141 (Erie County, New York)
- County Route 141 (Herkimer County, New York)
- County Route 141 (Niagara County, New York)
- County Route 141 (Rensselaer County, New York)
- County Route 141 (Sullivan County, New York)
- Delaware Route 141
- Farm to Market Road 141
- Georgia State Route 141
- Illinois Route 141
- Indiana State Road 141
- Iowa Highway 141
- Japan National Route 141
- K-141 (Kansas highway)
- Kentucky Route 141
- Louisiana Highway 141
- Maine State Route 141
- Malaysia Federal Route 141
- Massachusetts Route 141
- Missouri Route 141
- Montana Highway 141
- National Highway 141 (India)
- National Route 141 (Costa Rica)
- New Hampshire Route 141
- New York State Route 141
- North Carolina Highway 141
- Ohio State Route 141
- Oklahoma State Highway 141
- Ontario Highway 141
- Oregon Route 141
- Pennsylvania Route 141
- Prince Edward Island Route 141
- Puerto Rico Highway 141
- Quebec Route 141
- Tennessee State Route 141
- Texas State Highway 141
- Texas State Highway Loop 141
- U.S. Route 141
- Utah State Route 141
- Utah State Route 141 (1933-1969)
- Vermont Route 141
- Virginia State Route 141
- Virginia State Route 141 (1923-1928)
- Virginia State Route 141 (1933-1943)
- Virginia State Route 141 (pre-1933)
- Virginia State Route 141Y
- Washington State Route 141
- Wisconsin Highway 141 (pre-1926)