Saint Bernice, IndianaSaint Bernice is an unincorporated census-designated place in Helt Township, Vermillion County, in the U.S. state of Indiana. It had a population of 646 at the 2010 census.HistoryA post office has been in operation at Saint Bernice since 1867. The plat was filed in 1905. The origin of the name Saint Bernice is obscure.EducationIt is in the South Vermillion Community School Corporation. That school district operates South Vermillion High School.