Sprague
- Achsa W. Sprague
- Andrew Sprague
- Bud Sprague
- Burr Sprague
- Carl T. Sprague
- Charles Sprague (disambiguation)
- Clifton Sprague
- David Sprague
- E. Carleton Sprague
- Ed Sprague Jr.
- Ed Sprague Sr.
- Edward Spragge
- Elmer Sprague
- Erik Sprague
- Ernest Sprague
- Ezra T. Sprague
- Farah Sprague
- Frank J. Sprague
- Frank Lee Sprague
- Franklin B. Sprague
- George Sprague
- Homer Sprague
- Howard Sprague
- Isaac Sprague
- Isaac W. Sprague
- J. Russell Sprague
- Jack Sprague
- Jake Sprague
- Jo Ann Sprague
- John Allison Sprague
- John W. Sprague
- Ken Sprague
- Ken Sprague (cartoonist)
- L. Sprague de Camp
- Lucian Sprague
- Lucy J. Sprague
- Lucy Sprague Mitchell
- M. Estella Sprague
- Martyn Sprague
- Montgomery County, Alabama
- Peleg Sprague (Maine politician)
- Peleg Sprague (New Hampshire politician)
- Peter Sprague
- R. B. Sprague
- Richard E. Sprague
- Robert C. Sprague
- Robert Sprague (racing driver)
- Roderick Sprague
- Roland Sprague
- Royal Sprague
- Spragg (disambiguation)
- Spragge (disambiguation)
- Sprague (towboat)
- Sprague Avenue (Spokane, Washington)
- Sprague Cleghorn
- Sprague Electric
- Sprague Field
- Sprague Grayden
- Sprague Lake (Colorado)
- Sprague Mountain
- Sprague River (Maine)
- Sprague River (Oregon)
- Sprague, Connecticut
- Sprague, Manitoba
- Sprague, Missouri
- Sprague, Nebraska
- Sprague, Washington
- Sprague, West Virginia
- Sprague, Wisconsin
- Ted Sprague
- Thomas Archibald Sprague
- Thomas Bond Sprague
- Thomas L. Sprague
- W. G. R. Sprague
- William Sprague (disambiguation)