| Club | Sport | League | Status |
| Detroit Drive | Arena football | Arena Football League | Became the Massachusetts Marauders for the 1994 season, then was suspended for three years. |
| Detroit Fury | Arena football | Arena Football League | Franchise terminated September 20, 2004 |
| Grand Rapids Rampage | Arena football | Arena Football League | Franchise terminated March 5, 2010. |
| Detroit Stars | Baseball | Negro National League, 2nd Negro National League, Negro American League | The team ceased operations in 1960 |
| Detroit Wolverines | Baseball | National League | Played 1881–1888. Disbanded following the 1888 season; NL champions and "World Series" champions, 1887 |
| Kalamazoo Kings | Baseball | Minor League Baseball, Frontier League | Ceased operations in the 2011 season |
| Oakland County Cruisers | Baseball | Minor League Baseball, Frontier League | Moved to London, Ontario in 2012 and became the London Rippers |
| Detroit Shock | Basketball | Women's National Basketball Association | Moved to Tulsa, Oklahoma and became the Tulsa Shock; would move again to the Dallas–Fort Worth metroplex and are now the Dallas Wings. |
| Detroit Gems | Basketball | National Basketball League | Moved to Minneapolis and became the Minneapolis Lakers; would move again to Los Angeles and are now the Los Angeles Lakers |
| Detroit Falcons | Basketball | Basketball Association of America | Defunct |
| Michigan Mayhem | Basketball | Continental Basketball Association | Disbanded after 2005-2006 season |
| Holland Dream | Basketball | Independent Basketball Association | |
| Battle Creek Flight | Basketball | Independent Basketball Association | |
| Battle Creek Knights | Basketball | Premier Basketball League | |
| Detroit Panthers | Basketball | Premier Basketball League | |
| Mid-Michigan Destroyers | Basketball | Premier Basketball League | |
| Detroit Heralds/Tigers/Panthers/Wolverines | Football | National Football League | Defunct |
| Detroit Demolition | Football | Independent Women's Football League | |
| Detroit Wheels | Football | World Football League | Moved to Charlotte, North Carolina for one game, then disbanded in the middle of the 1974 season |
| Michigan Panthers | Football | United States Football League | Defunct |
| Flint Generals | Ice hockey | International Hockey League | Disbanded in 2010 when IHL merged into the AHL. |
| Michigan Stags | Ice hockey | World Hockey Association | Moved to Baltimore and became the Baltimore Blades for the rest of the team's existence |
| Detroit Vipers | Ice hockey | International Hockey League | Disbanded when IHL folded |
| Port Huron IceHawks | Ice hockey | International Hockey League | |
| St. Clair Shores Fighting Saints | Ice hockey | Federal Hockey League | Relocated to Kingsville, Ontario |
| Saginaw Sting | Indoor football | American Indoor Football | |
| Battle Creek Crunch | Indoor football | Continental Indoor Football League | |
| Detroit Thunder | Indoor football | Continental Indoor Football League | |
| Flint Phantoms | Indoor football | Continental Indoor Football League | |
| Kalamazoo Xplosion | Indoor football | Continental Indoor Football League | |
| Motor City Reapers | Indoor football | Continental Indoor Football League | |
| Muskegon Thunder | Indoor football | Continental Indoor Football League | |
| Port Huron Patriots | Indoor football | Continental Indoor Football League | |
| Port Huron Pirates | Indoor football | Continental Indoor Football League | |
| Port Huron Predators | Indoor football | Continental Indoor Football League | |
| Flint Flames | Indoor football | Indoor Football League | |
| West Michigan ThunderHawks | Indoor football | Indoor Football League | |
| Detroit Caesars | Softball | American Professional Slo-Pitch League | Disbanded in 1979. |
| Detroit Auto Kings | Softball | North American Softball League | Disbanded in 1980. |
| Detroit Ignition | Indoor soccer | Xtreme Soccer League | League folded in 2009 |
| Detroit Safari | Indoor soccer | Continental Indoor Soccer League | League folded in 1997. |
| Detroit Lightning | Indoor soccer | Professional | Relocated in 1980 to become the San Francisco Fog (MISL) |
| Detroit Express | Soccer | North American Soccer League | 1981, Moved to become Washington Diplomats, Lasted 1 year. League folded in 1984 |
| Kalamazoo Kingdom | Soccer | USL Premier Development League | Folded in 2006. |
| Lansing Ignite FC | Soccer | USL League One | Folded |
| Michigan Hawks | Soccer | W-League | Folded after the 2008 season. |
| Michigan Phoenix | Soccer | Women's Premier Soccer League | Left the WPSL and terminated in 2006 |
| West Michigan Edge | Soccer | USL Premier Development League | Folded after the 2008 season. |
| West Michigan Firewomen | Soccer | W-League | |
| Grand Rapids Chicks | Women's baseball | All-American Girls Professional Baseball League | League folded in 1954. |
| Kalamazoo Lassies | Women's baseball | All-American Girls Professional Baseball League | League folded in 1954. |
| Muskegon Belles | Women's baseball | All-American Girls Professional Baseball League | League folded in 1954. |
| Muskegon Lassies | Women's baseball | All-American Girls Professional Baseball League | Moved to Kalamazoo in 1950. |