Sirukumab


Sirukumab is a human monoclonal antibody designed for the treatment of rheumatoid arthritis. It acts against the proinflammatory cytokine Interleukin 6.
Sirukumab is currently under development by Johnson & Johnson's subsidiary Centocor.

Clinical trials

Rheumatoid arthritis

It has started clinical trials. and reported some phase II results.
In December 2015 three phase III trials were collecting data.
By Feb 2017 SIRROUND-D was considered to have met both co-primary endpoints.

Research

The drug was previously under development for the treatment of depression.