Single-Molecule FRET Analysis of Protein-DNA Complexes


Single-Molecule FRET Analysis of Protein-DNA Complexes is a scholarly work by Mike Heilemann and Achillefs N Kapanidis, published in 2009 in ''Methods in Molecular Biology''. The main subjects of the publication include chemistry, biophysics, Förster resonance energy transfer, deoxyribonucleic acid, cryogenic electron microscopy, failure analysis, molecule, Single-molecule FRET, computational biology, and DNA nanotechnology. The authors present a single-molecule method for studying protein-DNA interactions based on fluorescence resonance energy transfer (FRET) and alternating-laser excitation (ALEX) of single diffusing molecules.

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