List of number-one hits of 2021 (Germany)
The GfK Entertainment charts are record charts compiled by GfK Entertainment on behalf of the German record industry. They include the "Single Top 100" and the "Album Top 100" chart. The chart week runs from Friday to Thursday, and the chart compilations are published on Tuesday for the record industry. The entire top 100 singles and top 100 albums are officially released the following Friday by GfK Entertainment. The charts are based on sales of physical singles and albums from retail outlets as well as permanent music downloads.
Number-one hits by week
| Issue date | Song | Artist | Ref. | Album | Artist | Ref. |
| 1 January | "All I Want for Christmas Is You" | Mariah Carey | Die Helene Fischer Show - Meine schönsten Momente Vol. 1 | Helene Fischer | ||
| 8 January | "Angst" | Apache 207 | Power Up | AC/DC | ||
| 15 January | "Highway" | Katja Krasavice featuring Elif | Splitter aus Glück | Daniela Alfinito | ||
| 22 January | "Ohne dich" | Kasimir1441 featuring Badmómzjay and Wildbwoys | Inhale/Exhale | LX | ||
| 29 January | "Ohne dich" | Kasimir1441 featuring Badmómzjay and Wildbwoys | Natural Born Killas | Asche and Kollegah | ||
| 5 February | "Ohne dich" | Kasimir1441 featuring Badmómzjay and Wildbwoys | Eure Mami | Katja Krasavice | ||
| 12 February | "Ohne dich" | Kasimir1441 featuring Badmómzjay and Wildbwoys | Medicine at Midnight | Foo Fighters | ||
| 19 February | "Wellerman" | Nathan Evans | Summer in Berlin | Schiller | ||
| 26 February | "Madonna" | Bausa featuring Apache 207 | Aghori | Kool Savas | ||
| 5 March | "Wellerman" | Nathan Evans | Detroit Stories | Alice Cooper | ||
| 12 March | "Wellerman" | Nathan Evans | Manifest | King Orgasmus One | ||
| 19 March | "Wellerman" | Nathan Evans | Liebe macht Monster | Eisbrecher | ||
| 26 March | "Wellerman" | Nathan Evans | Hello! | Maite Kelly | ||
| 2 April | "Wellerman" | Nathan Evans | Widder | Fler | ||
| 9 April | "Wellerman" | Nathan Evans | Naosu | Sierra Kidd | ||
| 16 April | "Wellerman" | Nathan Evans | Ciao! | Giovanni Zarrella | ||
| 23 April | "Wellerman" | Nathan Evans | Jetzt erst recht! | Ben Zucker | ||
| 30 April | "Best Friend " | Saweetie featuring Doja Cat and Katja Krasavice | Puro Amor | Broilers | ||
| 7 May | "Wellerman" | Nathan Evans | Stay High | Ufo361 | ||
| 14 May | "Extasy" | Bonez MC featuring Frauenarzt | Vielleicht irgendwann | Wincent Weiss | ||
| 21 May | "Ich darf das" | Shirin David | Sampler 5 | 187 Strassenbande | ||
| 28 May | "Ich darf das" | Shirin David | Aus dem Licht in den Schatten zurück | Kontra K | ||
| 4 June | "Rosenkrieg" | Loredana and Mozzik | Rap über Hass | K.I.Z | ||
| 11 June | "Good 4 U" | Olivia Rodrigo | 20 | No Angels | ||
| 18 June | "Good 4 U" | Olivia Rodrigo | Neue Welt | Azet | ||
| 25 June | "Beggin'" | Måneskin | Helloween | Helloween | ||
| 2 July | "Sommergewitter" | Pashanim | HeimatLiebe | Kastelruther Spatzen | ||
| 9 July | "Lieben wir" | Shirin David | Das ist alles von der Kunstfreiheit gedeckt | Danger Dan | ||
| 16 July | "Bad Habits" | Ed Sheeran | Freiheit | Die Amigos | ||
| 23 July | "Bad Habits" | Ed Sheeran | Zukunft | RAF Camora | ||
| 30 July | "Blaues Licht" | RAF Camora featuring Bonez MC | Asozialer Marokkaner | Farid Bang | ||
| 6 August | "Bad Habits" | Ed Sheeran | Happier Than Ever | Billie Eilish | ||
| 13 August | "Bad Habits" | Ed Sheeran | Trip | Cro | ||
| 20 August | "Auf & ab" | Montez | MDNA | Genetikk | ||
| 27 August | "Enter Sandman" | Metallica | Complex Happenings Reduced to a Simple Design | Leoniden | ||
| 3 September | "Stay" | The Kid Laroi and Justin Bieber | Alles was du brauchst | Beatrice Egli | ||
| 10 September | "Mandarinen" | Shindy | Senjutsu | Iron Maiden | ||
| 17 September | "2CB" | RAF Camora featuring Luciano | Metallica | Metallica | ||
| 24 September | "Pussy Power" | Katja Krasavice | So weit | Peter Maffay | ||
| 1 October | "Stay" | The Kid Laroi and Justin Bieber | Dunkel | Die Ärzte | ||
| 8 October | "Kapitel II Vodka" | Apache 207 | Zukunft | RAF Camora | ||
| 15 October | "Shivers" | Ed Sheeran | Wenn die Kälte kommt | Santiano | ||
| 22 October | "Easy on Me" | Adele | Rausch | Helene Fischer | ||
| 29 October | "Shivers" | Ed Sheeran | Rausch | Helene Fischer | ||
| 5 November | "Be A Hoe/Break A Hoe" | Shirin David and Kitty Kat | = | Ed Sheeran | ||
| 12 November | "Raindrops" | Katja Krasavice and Leony | Voyage | ABBA | ||
| 19 November | "Der letzte Song " | Kummer featuring Fred Rabe | Voyage | ABBA | ||
| 26 November | "Easy on Me" | Adele | 30 | Adele | ||
| 3 December | "All I Want for Christmas Is You" | Mariah Carey | Voyage | ABBA | ||
| 10 December | "All I Want for Christmas Is You" | Mariah Carey | Servant of the Mind | Volbeat | ||
| 17 December | "All I Want for Christmas Is You" | Mariah Carey | 20 Jahre – Wir schaffen Deutsch.Land | Frei.Wild | ||
| 24 December | "Last Christmas" | Wham! | Nur | Fynn Kliemann | ||
| 31 December | "Last Christmas" | Wham! | Kontrollierte Anarchie | Philipp Burger |