Sergey Piletsky


Sergey Piletsky is a professor of Bioanalytical Chemistry and the Research Director for School of Chemistry, University of Leicester, United Kingdom.

Education

Sergey graduated from Kyiv University, Ukraine, obtaining an MSc in chemistry in 1985 and researched on synthesis of the polymers selective for nucleic acids, for which he was awarded with a PhD in 1991. Cranfield University awarded Sergey with a DSc for his work on molecularly imprinted polymers for diagnostics applications.

Awards

Sergey is a recipient of Royal Society Wolfson Research Merit Award, Leverhulme Trust Fellowship, DFG Fellowship from the Institute of Analytical Chemistry, Award of President of Ukraine, and Japan Society for Promotion of Science and Technology Fellowship.

Research

Sergey's work in molecular imprinting focuses on: the fundamental study of the recognition properties of molecularly imprinted polymers; the development of sensors and assays for environmental and clinical analysis; and the development of molecularly imprinted polymer nanoparticles for theranostic applications.
Sergey introduced computational design into the field of molecular imprinting, by scientifically demonstrating that non-covalent interaction between the template molecule and polymer is through the technique known as 'bite and switch' wherein functional groups first non-covalently bond with the binding site, but during the rebinding step, the polymer matrix forms irreversible covalent bonds with the target molecule. A number of research groups around the world follow his ideas in developing functional imprinted polymers for a variety of applications.

Notable publications

  • Surface-grafted molecularly imprinted polymers for protein recognition, A Bossi, SA Piletsky, EV Piletska, PG Righetti, APF Turner, Analytical chemistry 73, 5281-5286
  • Electrochemical sensor for catechol and dopamine based on a catalytic molecularly imprinted polymer-conducting polymer hybrid recognition element, Dhana Lakshmi, Alessandra Bossi, Michael J Whitcombe, Iva Chianella, Steven A Fowler, Sreenath Subrahmanyam, Elena V Piletska, Sergey A Piletsky, Analytical Chemistry 81, 3576-3584
  • Piletsky S.A., Turner A.P.F.. New generation of chemical sensors based on molecularly imprinted polymers, in: Molecular imprinting of polymers, S. Piletsky and A.P.F. Turner, Landes Bioscience, Georgetown, TX, USA

Notable patents

  • Rationally Designed Selective Binding Polymers, Publication number: 20100009859, Inventors: Sergey A. Piletsky, Olena Piletska, Khalku Karim, Coulton H. Legge, Sreenath Subrahmanyam
  • Electrochemical Sensor Publication number: 20210239643, Inventors: Sergey Piletsky, Omar Sheej Ahamad, Alvaro Garcia Cruz
  • Polymerisation method, polymers and uses thereof Publication number: 20060122288, Inventors: Sergey Piletsky, Olena Piletska, Anthony Turner, Khalku Karim, Beining Chen
  • Methods and Kits for determining binding sites Publication number: 20200033356, Inventors: Sergey Piletsky, Elena Piletska, Francesco Canfarotta, Don Jones
  • Photoreactor and Process for Preparing MIP Nanoparticles Publication number: 20140228472, Inventors: Sergey Piletsky, Olena Piletska, Antonio Guerreiro, Michael Whitcombe, Alessandro Poma