SERC
- Central Electricity Regulatory Commission
- Circ (disambiguation)
- Emergency Planning and Community Right-to-Know Act
- Kyushu University
- Phosphoserine transaminase
- SERC Reliability Corporation
- Science Education Resource Center
- Science and Engineering Research Council
- Smithsonian Environmental Research Center
- Solar Energy Research Center
- South Eastern Regional College
- Stock Exchange Rifle Club
- Sérc