Senator Clarke
- Archibald S. Clarke
- Eugene Clarke
- Frank Gay Clarke
- George L. Clarke
- George W. Clarke (Washington politician)
- Hansen Clarke
- James M. Clarke
- James Paul Clarke
- John Blades Clarke
- John Clarke (Michigan politician)
- John Hopkins Clarke
- John Jones Clarke
- Kathryn Clarke (politician)
- S. D. Clarke
- Terrel E. Clarke