Schisandrin

Schisandrins are a group of bioactive chemical compounds found in Schisandra rubriflora, Schisandra sphenanthera, and Schisandra chinensis. Schizandrin is a lignan.

IUPAC">IUPAC nomenclature of chemistry">IUPAC Name*

3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclohexadeca-1,2,4,6,12,14-hexaen-9-ol
*''Computed by Lexichem TK 2.7.0 ''

CAS Common Chemistry

7432-28-2

Molecular Formula

C24H32O7

Molecular Weight

432.5

PubChem CID

23915

Characteristics

Schisandra chinensis berries, originally a component of traditional herbal medicine in China, Korea, and other east Asian countries, are also valuable agents in modern phototherapy. S. chinensis berry preparations, including extracts and their chemical components, demonstrate anti-cancer, hepatoprotective, anti-inflammatory, and antioxidant properties, among others. These valuable properties, and their therapeutic potential, are conditioned by the unique chemical composition of S. chinensis berries, particularly their lignan content. About 40 of these compounds, mainly dibenzocyclooctane type, were isolated from S. chinensis. The most important bioactive lignans are schisandrin, schisandrin B, schisantherin A, schisantherin B, schisanhenol, deoxyschisandrin, and gomisin A. The present work reviews newly-available literature concerning the cardioprotective potential of S. chinensis berries and their individual components. It places special emphasis on the cardioprotective properties of the selected lignans related to their antioxidant and anti-inflammatory characteristis.
Examples include: