SAPO
- Cochabamba Department
- Darién Province
- Lindelwa Sapo
- Mount Sapo
- Mão Morta
- SAPO (company)
- SAPO (computer)
- Sapio (disambiguation)
- Sapo National Park
- Sapo language
- South African Port Operations
- South African Post Office
- Specialized Anti-Corruption Prosecutor's Office
- Swedish Security Service
- Toad in the hole (game)