Sapelovirus


Sapelovirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Pigs and simians serve as natural hosts. There are two species in this genus.

Taxonomy

The genus contains the following species:
  • Sapelovirus anglia, Porcine sapelovirus
  • Sapelovirus besimi, Simian sapelovirus

Structure

Viruses in Sapelovirus are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 7.5-8.3kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
SapelovirusIcosahedralPseudo T=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and viroporins. Pigs and simians serve as natural hosts.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
SapelovirusBirds-Cell receptor endocytosisLysisCytoplasmCytoplasmUnknown