Santee
- Lake Santee, Indiana
- Santee (Corbin, Virginia)
- Santee (South Carolina)
- Santee (film)
- Santee (plumbing)
- Santee (surname)
- Santee Branch
- Santee Canal
- Santee Dakota
- Santee Education Complex
- Santee National Wildlife Refuge
- Santee River
- Santee Sioux Reservation
- Santee Smith
- Santee State Park
- Santee station
- Santee, California
- Santee, Nebraska
- Santee, South Carolina
- Santi (disambiguation)
- Santy
- USS Santee