Samuel Barnes

• Samuel Barnes, one half of the Trackmasters and a rapper known also as Red Hot Lover Tone
• Samuel Barnes (Australian politician), member of the Victorian Parliament
• S. A. G. Barnes, member of the Legislative Assembly of Alberta
• Samuel H. Barnes, American politician from New York
• Sam Barnes (baseball), American baseball player
• Sam Barnes (footballer, born 1991), English football centre-back
• Sam Barnes (footballer, born 2001), English football centre-back for Blackburn Rovers