Sam
- Auger electron spectroscopy
- Bacterial phyla
- Boston Beer Company
- Cen (surname)
- Chatbot
- I2P
- Magellanic spiral
- Microsoft Sam
- Phytelephas seemannii
- S-Adenosyl methionine
- SAM (file format)
- SAM (vehicles)
- SAM Colombia
- SAM Coupé
- SAM Records
- SAM card
- SAMtools
- Sahabat Alam Malaysia
- Salamo Airport
- Sam (1967 film)
- Sam (1973 TV series)
- Sam (1978 TV series)
- Sam (1986 film)
- Sam (2021 film)
- Sam (Book of Mormon)
- Sam (Olivia Newton-John song)
- Sam (Osvajači album)
- Sam (army dog)
- Sam (given name)
- Sam (horse)
- Sam (koala)
- Sam (mascot)
- Sam (novel)
- Sam (orangutan)
- Sam (surname)
- Sam (text editor)
- Sam (ugly dog)
- Sam (Škabo album)
- Sam FM (disambiguation)
- Sam Maguire Cup
- Sam Ziwa
- Sam language
- Sam languages
- Sam, Benin
- Sam, Boulkiemdé
- Sam, Bourzanga
- Sam, Iran
- Sam, Kongoussi
- Sam. (disambiguation)
- Samantha Ruth Prabhu
- Samaritan Aramaic language
- Samoa
- Sample Analysis at Mars
- Samsø
- Sandy Area Metro
- Scanning acoustic microscope
- Scheduled monument
- Schule am Meer
- Scientific Advice Mechanism
- Seattle Art Museum
- Secure access module
- Security Account Manager
- Segmental arterial mediolysis
- Self-assembled monolayer
- Sequential access memory
- Serve America Movement
- Serviceable available market
- Shared appreciation mortgage
- Shem
- Shen (surname)
- Shoot apical meristem
- Significance analysis of microarrays
- Simulation for Automatic Machinery
- Singapore Art Museum
- Small article monitor
- Social accounting matrix
- Society of American Magicians
- Società Aerea Mediterranea
- Software Automatic Mouth
- Software asset management
- Sorting and assembly machinery
- South Australian Museum
- South Australian Music Awards
- Southern Annular Mode
- Special administrative measure
- Split attraction model
- Spore photoproduct lyase
- Stop action magnet
- Strongside linebacker
- Surface-to-air missile
- Sustained Acoustic Medicine
- Swimming Association of Maldives
- Swinging Atwood's machine
- Syriac Abbreviation Mark
- Syskey
- System for Award Management
- Sām
- Tala (music)
- Teton County, Idaho
- Tropical Storm Sam
- Uncle Sam
- Unsinkable Sam