Salih al-Ali was born in 1883 to a family of Alawite notables from al-Shaykh Badr, in the Syrian Coastal Mountain Range in northwest. He reportedly clashed with the Ottomans in 1918 before their withdrawal from Syria, killing two Ottoman soldiers who were harassing a wife of his father. This act gained him a local reputation as a rebel. After his father's death, he built a shrine for him and reportedly performed miracles at the site, according to local legend.
The balance of power began to shift in favor of the French after they conquered Damascus, defeating a makeshift army at the Battle of Maysalun on 24 July 1920. Around this time al-Ali began collaborating, through Ibrahim Hananu's meditation, with Turkish Kemalist forces fighting the French occupation in southern Anatolia. A letter addressed directly to Mustafa Kemal in January 1921 asking for weapons for their common "jihad" against the French is preserved in the Turkish ATASE military archives in Ankara.