Saint Adrian
- Adrian of Nicomedia, Herculian Guard of the Roman Emperor Galerius
- Adrian of Canterbury, scholar and the Abbot of St Augustine's Abbey in Canterbury
- Adrian of Corinth, early Christian saint and martyr; see April 17
- Pope Adrian III
- Adrian of May, Scottish saint and martyr from the Isle of May, martyred by Vikings
- Adrian of Poshekhon, Russian Orthodox saint, hegumen of Dormition monastery in Yaroslavl region
- Adrian of Monza, Russian Orthodox saint, see May 5
- Adrian of Ondrusov, Russian Orthodox saint and wonder-worker
- San Adrian and hermitage, a landmark in the Way of St. James