STC
- Dynamic Stability and Traction Control
- Intel MCS-51
- Intercity STC
- Nortel F. C.
- S. Thomas' College, Mount Lavinia
- SHAPE Technical Centre
- STC Recordings
- Saint Theresa's College (disambiguation)
- Saskatchewan Transportation Company
- Scarborough Town Centre
- Scott Theological College
- SeeBeyond Technology Corporation
- Sengkang MRT/LRT station
- Sensitivity time control
- Sha Tin College
- Shakespeare Theatre Company
- Short-title catalogue
- Siaʻatoutai Theological College
- Silicon tetrachloride
- Singapore Traction Company
- Sistema de Transporte Colectivo
- Society for Technical Communication
- Solidaridad de Trabajadores Cubanos
- Sonic the Comic
- Sound transmission class
- South Tama County Community School District
- South Texas College
- South Thames Colleges Group
- South Tyneside College
- Southern Transitional Council
- Space Transport Corporation
- Space–time code
- Spike-triggered covariance
- St. Cloud Regional Airport
- St. Thomas' College, Matale
- Standard Telephones and Cables
- Standard test conditions
- Stewart Information Services Corporation
- Storage Technology Corporation
- Student Transportation of Canada
- Supplemental type certificate
- Sydney Theatre Company
- Sydney Turf Club
- The Soundtrack Channel