SSS
- Congregation of the Blessed Sacrament
- Daniel Sturridge
- Irlen syndrome
- List of MADLAX characters
- Liverpool F.C.
- Luis Suárez
- Mignonette (album)
- Omega baryon
- Planet of the Daleks
- Raheem Sterling
- Roblox
- SATS Security Services
- SS501
- SSS Defence
- SSS islands
- SSS*
- Salinity
- Scarborough Shooting Stars
- Selective Service System
- Senior Staff Sergeant
- Sensation Seeking Scale
- Serangoon Secondary School
- Shamir's Secret Sharing
- Sheerness-on-Sea railway station
- Sheffield Scientific School
- Shelby Sumpter Singleton
- Short Sharp Shock (band)
- Siassi
- Sick sinus syndrome
- Siding Spring Survey
- Sign Supported Speech
- Sign Systems Studies
- Sigue Sigue Sputnik
- Singapore Sports School
- Single-serving site
- Sisters of Social Service
- Sisyphus (hip hop group)
- Smithers Secondary School
- Smithfield-Selma School
- Soccer-specific stadium
- Social Security System (Philippines)
- Social security system
- Socialist Sunday School
- Solid State Survivor
- Solid-state storage
- Sonic Speed Simulator
- Southern Cross railway station
- Sovran Self Storage
- Sport Searching School
- Standard Scratch Score
- State Security Service (Nigeria)
- Subclavian steal syndrome
- Substructure search
- Subsurface scattering
- SunSet Swish
- Super Scalable System
- Super Special Stage
- Super SteadyShot
- Super soft X-ray source
- Superior sagittal sinus
- Sutton's Sign Symbol Sequence
- Svensk Socialistisk Samling
- Swedish Swing Society
- SweetSexySavage
- Súper Sábado Sensacional
- Trickbaby
- Triple-S Management Corporation