SSB
- Presidency of Defense Industries
- SSB (militia)
- Sashastra Seema Bal
- Scandinavian School of Brussels
- Secret Service Bureau
- Secure Scuttlebutt
- Services Selection Board
- Ship Submersible Ballistic
- Single-sideband modulation
- Single-strand break
- Single-stranded binding protein
- Site-specific browser
- Sjögren syndrome antigen B
- Smoke Signal Broadcasting
- Social Security Board (disambiguation)
- Societas Sanctae Birgittae
- Society of Systematic Biologists
- Society of the Sisters of Bethany
- Solid-state battery
- Sonic Soldier Borgman
- Special Service Battalion
- Speculative Store Bypass
- Spontaneous symmetry breaking
- Standard Southern British
- Statistics Norway
- Strategic Support Branch
- Stuttgarter Straßenbahnen
- Städtische Strassenbahn Bern
- Sugar-sweetened beverage
- Super Smash Bros.
- Super Smash Bros. (video game)
- Sustainable South Bronx
- Swedish School Beijing
- Swet Shop Boys