List of highways numbered 112
- A112 road
- Alabama State Route 112
- Arkansas Highway 112
- California State Route 112
- California State Route 61
- China National Highway 112
- Colorado State Highway 112
- Connecticut Route 112
- County Route 112 (Bergen County, New Jersey)
- County Route 112 (Fulton County, New York)
- County Route 112 (Niagara County, New York)
- County Route 112 (Rockland County, New York)
- County Route 112 (Suffolk County, New York)
- County Route 112 (Sullivan County, New York)
- County Route 112 (Wayne County, New York)
- County Route 112 (Westchester County, New York)
- D112 road
- Farm to Market Road 112
- Florida State Road 112
- Georgia State Route 112
- Indiana State Road 112
- Interstate 94
- K-112 (Kansas highway)
- Kentucky Route 112
- Lee County, Alabama
- List of National Roads in Latvia
- List of highways numbered 112S
- Louisiana Highway 112
- M-112 (Michigan highway)
- Maine State Route 112
- Maryland Route 112
- Massachusetts Route 112
- Minnesota State Highway 112
- Missouri Route 112
- National Highway 112 (India)
- National Route 112 (Costa Rica)
- Nebraska Highway 112
- New Brunswick Route 112
- New Hampshire Route 112
- New Mexico State Road 112
- New York State Route 112
- North Carolina Highway 112
- Ohio State Route 112 (disambiguation)
- Oklahoma State Highway 112
- Ontario Highway 112
- PA-112
- Pennsylvania Route 112
- Prince Edward Island Route 112
- Puerto Rico Highway 112
- Quebec Route 112
- R112 road (Ireland)
- Rhode Island Route 112
- Route 112 (Japan)
- S112 (Amsterdam)
- Santa Clara–Cienfuegos Road
- Tennessee State Route 112
- Texas State Highway 112
- U.S. Route 112
- U.S. Route 112 (Wisconsin)
- Utah State Route 112
- Vermont Route 112
- Virginia State Route 112
- Virginia State Route 112 (1923-1928)
- Virginia State Route 112 (1928-1933)
- Virginia State Route 112 (1933-1943)
- Washington State Route 112
- West Virginia Route 112
- Wisconsin Highway 112
- Wyoming Highway 112